The development of atherosclerotic plaques is associated with several clinical cardiovascular events. Although the dose applied in our study was 5-fold lower, our results agree with those reported by Zhang et al. It is rich in essential fatty acids, including omega-3 and omega-6, which are important for maintaining a healthy heart and brain. e., individuals with metabolic syndrome, would profit from a daily intake of 15–20 g of echium,”​ addd Kuhnt and her co-authors. Lees J: Incidence of weight loss in head and neck cancer patients on commencing radiotherapy treatment at a regional oncology centre.

The material was submitted to microtomy with a cut of 5 μm and stained with hematoxylin and eosin for histopathological evaluation [ 19]. Third, non-adherence to the dietary supplement did not lead to exclusion since the primary endpoint was analysed according to the intention-to-treat principle for which our trial was sufficiently powered. Considering the health effects of LC n-3 PUFA toward the reduction of cardiovascular disease (CVD) risk [ 4, 5], many industries have added eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) from marine oils to food formulations or supplements, aiming to explore this health claim. Nevertheless, the intervention proved ineffective in reducing weight loss during radio(chemo)therapy.For collection of secondary endpoint data, the study coordinator, assisted by a dietician specialised in oncology, assessed nutritional status of every patient at baseline (week 0, W0), mid-therapy (W4) and at treatment end (W7) by the Patient-Generated Subjective Global Assessment (PG-SGA), as this is considered the gold standard for evaluation of nutritional status in oncology [ 26– 28]. Its unique combination of SDA, ALA, and GLA [gamma-linolenic acid] is considered to be relevant in health-related nutrition. Sioen I, Devroe J, Inghels D, Terwecoren R, De Henauw S: The influence of n-3 PUFA supplements and n-3 PUFA enriched foods on the n-3 LC PUFA intake of Flemish women. In the United States, dietary supplements are regulated by the Food and Drug Administration (FDA) under the Dietary Supplement Health and Education Act (DSHEA). A comparable percentage of patients in both groups required hospitalisation for artificial nutritional support (I: 18.

However, although a significant decline in caloric intake – comparable with literature [ 57, 58] – was observed, no significant differences in caloric intake that could have had an impact on weight loss were seen between both groups.Among them, Echium oil provided the best results in terms of VLDL and total cholesterol reduction and contributed to the attenuation of hepatic steatosis. Fatty acids profile of the oils used in this study was analyzed by gas chromatography and is shown in Table 1. However, the preventive and therapeutic implications of SDA-rich echium oil remain to be fully determined.