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A recent meta-analysis on the effects of garlic supplements on blood pressure, including 20 trials and >900 participants, revealed a significant effect of garlic on blood pressure, with an average decrease in SBP of 8.6 mm and 6.1 mm in DBP in hypertensive subjects (n=14 trial arms, n=468 participants) ( 4). Furthermore, as high blood pressure has been linked to the dysbiosis of gut microbiota, both in animal and human studies, with a significant lower microbial richness and diversity in hypertensive subjects compared to normotensive subjects ( 18), we investigated the effects of Kyolic garlic on the microbiome in our most recent clinical study, the GarGIC trial ( 8). In general, a higher relative abundance/bacterial mass/microbial richness and a diversity of microbial species is associated with better health ( 18– 20).
if your blood pressure is consistently above 140/90mmHg (or 135/85mmHg at home) and your risk of other problems is high – you'll be offered medicine to lower your blood pressure, in addition to lifestyle changes
High blood pressure in older people
Latest research has provided new evidence for Kyolic aged garlic extract to improve central haemodynamic measures, including central blood pressure and pulse pressure, and pulse wave velocity, a measure for arterial stiffness, regarded as important predictors for cardiovascular disease. Kyolic aged garlic extract has the potential to reverse the ageing of the arteries and therefore, arterial stiffness by approximately 5 years, as evidenced by a mean reduction in pulse wave velocity by 0.7 m/sec within 3 months. Whatever your age or ability, regular exercise can have many beneficial impacts to your overall health, alongside your heart’s health. Statistics show that it can reduce your risk of major illness, heart disease, diabetes, stroke, and cancer by up to 30% 4. Try taking as little as 20 minutes per day to exercise – this could be a stroll, a run, or taking a yoga class. Whatever your exercise activity may be, it can contribute to the health of your heart. Both what you eat and how much of it matter. Try to limit the amount of food you eat at each meal by consuming more low-calorie and nutritious foods, such as fruits and vegetables. The high mineral and vitamin content of fruits and vegetables promotes heart health. B1, which is present in foods like cauliflower, oranges, potatoes, asparagus, kale, and many others, helps to support healthy heart function. With its prebiotic properties, and the source of intracellular H 2S ( 16, 21), garlic has the potential to modulate the gut microbiota ( 22), and to restore the microbiota biofilm and mucus production ( 23). The timeframe for changes to be observed in the composition of the gut microbiota with dietary supplementation is relatively short, as shown in a 4-week study of patients with irritable bowel syndrome taking probiotics daily ( 24). In addition, the consumption of probiotics has been shown to significantly reduce blood pressure, in particular in trials of >8 weeks duration (meta-analysis of 9 RCTs involving 534 patients) ( 25).
In our third ‘AGE at Heart’ trial we found Kyolic to be effective in reducing peripheral blood pressure, as well as central blood pressure, central pulse pressure, pulse wave velocity and arterial stiffness ( 7). Central hemodynamic measures, such as central blood pressure, pulse wave velocity, pulse pressure and arterial stiffness, are regarded as more important predictors than peripheral blood pressure for cardiovascular disease risk ( 11, 12). Arterial stiffness, an indicator of the flexibility of the arteries, increases with age through the loss of intact elastin and collagen fibres in the arterial wall ( 13, 14), which also contributes to increased blood pressure ( 15). Kyolic aged garlic extract has been shown to be effective in reducing arterial stiffness, which in turn is related to better heart health and aerobic fitness, while the risk of cardiovascular disease is reduced ( 7, 8, 12). Your doctor will carry out some blood and urine tests, and ask questions about your health to determine your risk of other problems: Food Supplement Ingredients Potassium Chloride, Magnesium Oxide, Bulking Agents (Cellulose, Cross-Linked Sodium Carboxymethyl Cellulose), Anti-Caking Agents (Mono- and Diglycerides of Food Fatty Acids, Magnesium Salts of Food Fatty Acids, Silicon Dioxide, Talcum), Hydrogenated Palm Oil, Coating (Hydroxypropylmethyl Cellulose, Polyethylenglycol), Ferrous Fumarate, Vitamin B6 (as Pyridoxine Hydrochloride), Zinc Oxide, Vitamin B12 (as Cyanocobalamin), Colour Titanium Dioxide
Rewards For Life
Your GP can advise you about changes you can make to your lifestyle and discuss whether they think you'd benefit from medicine. You may need to take blood pressure medicine for the rest of your life. But your doctor might be able to reduce or stop your treatment if your blood pressure stays under control for several years. In addition to the beneficial effects of garlic supplements on blood pressure, we, as well as others have found that Kyolic aged garlic extract is effective in rejuvenating the arteries, as evidenced by a reduction in pulse wave velocity ( 7, 8, 12). While arterial stiffness increases naturally with age by an average of 1.43 m/sec pulse wave velocity in 10 years ( 13, 14), our findings suggested that Kyolic aged garlic extract has the potential to reverse the ageing of the arteries and therefore, arterial stiffness by approximately 5 years, as evidenced by a mean reduction in pulse wave velocity by 0.7 m/sec within 3 months ( 8).
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