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Sample was not taken at the correct time (for combined screening CRL between 45.0mm and 84.0mm, for quadruple screening head circumference ( HC) greater than 101.0mm up to 20 weeks and zero days). Denominator: number of confirmed cytogenetic diagnoses of T21, T18, T13 following any result (higher or lower chance) from the combined test Down’s syndrome (T21) quadruple test The private screening: important information leaflet provides information for people who ask about private screening options. Non-invasive prenatal screening test (NIPT) The FASP handbook brings together national guidance, information and processes that relate to the FASP screening pathways. Denominator: number of pregnant women booked for antenatal care during the reporting period, excluding women who:
Certificates of Good Standing (dated within three months of the application date), if regulated by another regulator. National performance of ST4b (see standard STC-S05) in Q2 was 63.9%, lower than the previous quarter. The trend graph below shows England ST4b performance since the KPI was first published in Q1 2019 to 2020. Thresholds have not yet been set for this KPI. To provide assurance that screening is offered to everyone who is eligible and each woman who accepts screening has a conclusive screening result. Definition Screening for 11 physical conditions as part of the 20-week scan is offered to all pregnant women and takes place between 18⁺⁰ and 20⁺⁶ weeks of pregnancy. Scans can be completed up to 23⁺⁰ weeks of pregnancy. Conditions screened for
National performance of NB2 (see standard NBS-S06) in Q1 was 2.2%, higher than the previous quarter. The trend graph below shows that England NB2 performance is above the acceptable threshold of 2%. NB2 is a KPI where a lower performance is better. This report should be read in conjunction with the full key performance indicator ( KPI) data tables published each quarter. 1. Fetal anomaly screening 1.1 KPI FA2: coverage: fetal anomaly ultrasound Date standard last updated: April 2018 FASP-S03a: test: screen positive rate T21, T18, T13 screening Description
Denominator: number of samples received for QFPCR testing where the indication for genetic testing is a suspected or confirmed anomaly detected on the 18 weeks plus 0 days to 20 weeks plus 6 days fetal anomaly ultrasound undertaken in the reporting period.The numerator and denominator exclude congenitally corrected transposition of the great arteries ( TGA). Recommendations are based on internationally recognised criteria and a rigorous evidence review process.
FA4 was introduced in 2020 to 2021. New KPIs are not published in the first year of data collection. This time is used to improve the data quality and completeness, by revising the definition, adding clarity and / or setting thresholds as required. After this time we will review the data with the aim of publishing it from the following year. 2. Infectious diseases in pregnancy screening 2.1 KPI ID1: HIV coverage All identified babies must be notified by providers to NCARDRS as are other structural and chromosomal anomalies. Data items on dates and cardiac findings of fetal anomaly scans, repeat scans, expected date of delivery, date of booking to be completed/validated by relevant service of booking/screening. Denominator excludes initial samples received that are not fit for analysis and a repeat sample is requested, or are received with missing data required for calculating the result; this delays reporting. This standard is a measure of the laboratory’s performance. Data collection and reportingStandard S08b excludes women with a suspected or confirmed fetal anomaly where the referral is to an obstetric ultrasound specialist locally for ongoing investigation and care (as clinically appropriate as per local pathway). The numerator and denominator include those completing the fetal anomaly scan from 18 weeks plus 0 days to 23 weeks plus 0 days of pregnancy.
National performance of NB2 (see standard NBS-S06) in Q4 was 2.4%, lower than the previous quarter. The trend graph below shows that England NB2 performance is above the acceptable threshold of 2%. NB2 is a KPI where a lower performance is better. Information about the screening tests should be provided to each pregnant woman so she is able to make a personal informed choice about the tests. Denominator: number of T21, T18, T13 screening samples received in the screening laboratory in the reporting period excluding samples received: The 20-week screening scan can be completed between 18 weeks and 0 days and 23 weeks plus 0 days weeks of pregnancy. For women between at or after 22 weeks plus 0 days and before or at 23 weeks plus 0 days, every effort must be made to accommodate the offer of the screening scan and they should be included in the denominator. In cases where the service is unable to offer the screening scan, they can be excluded. National performance of ST4b (see standard STC-S05) in Q1 was 68.4%, higher than the previous quarter. The trend graph below shows England ST4b performance since the KPI was first published in Q1 2019 to 2020. Thresholds have not yet been set for this KPI.
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