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Also, a 2-year cohort study found a 36% reduction in nonsteroidal anti-inflammatory drug (NSAID) use when taking 1,500 mg of crystalline glucosamine daily ( 8). Tech Workers: texting, typing, tapping—though the life of a tech enthusiast seems fairly injury-free, tech usage does accumulate a significant amount of connective tissue strain.
Ultimately, no firm conclusions can be made on the effectiveness of glucosamine, chondroitin, or the two combined as a treatment for osteoarthritic pain or stiffness. Due to the large inconsistency in results and quality of available research, continued research is needed. Summary The supplement was discontinued and no further heart rhythm disturbances were noted in the six months that followed. Turmeric is full of polyphenols or antioxidants that are known to protect the body from free radicals that can cause mutations in cellular DNA. It also plays a role in healing the damage to the body that happens from environmental carcinogens. Turmeric is an ancient superfood that’s been used for thousands of years as both a herb and cooking ingredient. The bright yellow turmeric root extract has an active ingredient called curcumin, which can help promote healthy digestion. Use caution when taking medicinal doses of turmeric or curcumin at the same time as medicines with significant side effects (e.g. anticancer or immunosuppressant agents) or medicines with a narrow therapeutic index.
Combined with chondroitin, glucosamine has been shown in research to help mitigate synovial fluid inflammation to provide “efficient pain relief in similar level with tramadol, a narcotic analgesic.” The Combined Benefits of Glucosamine + Chondroitin
Prasad S, Aggarwal BB. Turmeric, the Golden Spice: From Traditional Medicine to Modern Medicine. In: Herbal Medicine: Biomolecular and Clinical Aspects. 2 nd Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 13. Much of joint pain can be attributed to inflammation of the synovia, making joint movement feel tender and painful.Additionally, anyone who is taking any prescribed medication, is pregnant or breastfeeding, or has any medical conditions should consult a healthcare professional before taking glucosamine. After 6 months, chondroitin sulfate led to similar pain scores as celecoxib and significantly lower scores than the placebo. Thus, the authors concluded that chondroitin sulfate may be an effective pain remedy for those with knee osteoarthritis pain ( 10).
That being said, glucosamine and chondroitin have been shown to inhibit the activation of inflammatory pathways in human synovial cells. These cells are responsible for producing synovial fluid components, or joint fluid ( 5). When taken orally, turmeric ( Curcuma longa) is usually well tolerated but most studies have been short. In the U.S., turmeric is best known as a spice. You might hear people say it in two ways: tur-mer-ik or too-mer-ik. It's one of the main ingredients in yellow curry powder. It also gives some mustards a more vibrant yellow color. People often use glucosamine to treat a wide variety of chronic inflammatory diseases, although scientific data to support this is limited. Interstitial cystitis Often, these common gastrointestinal effects are mild and occur at a similar rate with placebo and turmeric in clinical trials. Liver
Nutrition and Healthy Living
However, keep in mind that glucosamine is commonly derived from chitin — a compound found in shellfish. Therefore, those with a shellfish allergy should read the label carefully and opt for varieties made from cows or pigs ( 17). Another place to find turmeric at the grocery store is in the tea aisle. Many tea varieties include turmeric in their lists of ingredients. But you wouldn't know how much turmeric you're getting from drinking a prepared tea. This might lead to increased adverse effects, including myopathy (muscle weakness and/or pain), which is dose-dependent.
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